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Preventing end-stage renal disease in Thai newly-diagnosed severe lupus nephritis patients: cost-effectiveness of alternative drug regimens (research for development of the health benefit package under the Universal Coverage scheme)

Home > Research Projects > Strategy 3 : HTA Research > Preventing end-stage renal disease in Thai newly-diagnosed severe lupus nephritis patients: cost-effectiveness of alternative drug regimens (research for development of the health benefit package under the Universal Coverage scheme)

Project Code

11-303-2552

Research team

Researchers

Adun Mohara B.Pharm, M.Sc.(Health Economic)

Co - Researcher

Naiyana Praditsitthikorn, PhD.

Project Details

Strategies
Category
Support
Project duration

Start: - 2009
End: -

Contact
[email protected]

Project Status

Completed - 100%

Viewer: 1685

Publish date19 December 2011 12:10

Project Summary

The purpose of this study is to compare the cost-utility of each treatment option available today in order to determine the most cost-effective treatment compared with standard treatment in the social perspective. Research methodology is an economic evaluation by using the markov model to compare the cost and utility of treatment options of new patients with lupus nephritis class III and IV. The time frame of the study is from the treatment of patients until their death. The study found that the regimen of intravenous cyclophosphamide 1000 mg per month for six months followed by an oral dose of azathioprine 50 milligram per day for three consecutive years was the best option compared to other existing options. The treatment cost could be saved through the life-time treatment in one patient. The treatment was more effective in terms of the quality of life and the increase in years lived compared with the standard treatment.

Documents

Activity

Health Intervention and Technology Assessment Program Foundation
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