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Economic evaluation and feasibility analysis of using three-drug antiretroviral regimens as the standard regimens for the prevention of mother-to-child transmission of HIV in Thailand (in Thai language)

Home > Research Projects > Strategy 3 : HTA Research > Economic evaluation and feasibility analysis of using three-drug antiretroviral regimens as the standard regimens for the prevention of mother-to-child transmission of HIV in Thailand (in Thai language)

Project Code

11-301-2552

Research team

Researchers

Pitsaphun Werayingyong

Co - Researcher

Nittaya Phanuphak

Kulkanya Chokephaibulkit

Sarawut Boonsuk

Nipunporn Voramongkol

Nareeluk Kullert

Sripen Tantivess, PhD.

Yot Teerawattananon, PhD.

Wantanee kulpeng

Kakanang Tosanguan, BSPs.(Pharmaceutical Science)

Rukmanee Butchon, PhD.

Project Details

Strategies
Category
Support
Tags
Project duration

Start: - 2014
End: -

Contact
[email protected]

Project Status

Completed - 100%

Viewer: 2187

Publish date9 December 2011 03:55

Project Summary

Zidovudine (AZT) plus single dose nevirapine (AZT+sd-NVP) were provided to pregnant women with HIV infection who have CD4 > 200 cell/mm3 for preventing vertical transmission. However, three-drug regimen is provided to pregnant women with HIV infection regardless CD4 cell count in high resource countries. Mother to child transmission rate in pregnant women in the receiving three-drug regimen was lower than that in pregnant women receving AZT+sd-NVP. On the other hand three-drug regimen is expensive so it could be a finance handle in limited resource countries. The implement of the change is still to be determine. The objectives of this study are to evaluate the cost-effectiveness of three-drug antiretroviral compared to AZT+sd-NVP and assess the feasibility of implementation of the use of three-drug antiretroviral regimen as the standard regimen for the prevention of mother-tochild transmission of HIV. The study shows that three-drug regimen is more cost-saving because it saves cost of treatment in newborn with HIV infection. The implementation of the three-drug regimen is feasible in the health care system in Thailand. Moreover, the adherence of three-drug regimen is good in pregnant women.

Documents

Activity

Health Intervention and Technology Assessment Program Foundation
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