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Highlights

  • This report provides practical guidance for developing or updating health technology assessment (HTA) guidelines, especially in low- and middle-income countries where HTA is increasingly used as a priority setting tool for healthcare resource allocation and achieving universal health coverage.
  • We provide context-dependent recommendations across 6 domains for HTA guideline development: setting goals, building a team, defining the stakeholder engagement plan, developing content, putting in place institutional arrangements, and evaluating guideline success.
  • Recommendations support the development and adoption of high-quality HTA guidelines that strengthen HTA institutionalization across different settings.

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